Impact of contouring methods on pre-treatment and post-treatment dosimetry for the prediction of tumor control and survival in HCC patients treated with selective internal radiation therapy

EJNMMI Research

Table 4 Spearman correlation between dose metrics calculated before (based on ^99mTc-MAA SPECT/CT; pre-treatment dose metrics)) and after SIRT (based on ⁹⁰Y-microspheres PET/CT; post-treatment dose metrics) in patients receiving resin microspheres (n = 25) and glass microspheres (n = 23)

	Pre-treatment dose metrics	Post-treatment dose metrics	Resin microspheres (n = 25)		Glass microspheres (n = 23)
	Pre-treatment dose metrics	Post-treatment dose metrics	r	p	r	p
Scintigraphic-based contours	Dm-Pre-C_SPECT	Dm-Post-C_PET	0.85	< 0.0001	0.41	NS
	D70-Pre-C_SPECT	D70-Post-C_PET	0.81	< 0.0001	0.37	NS
MRI-based contours	Dm-Pre-C_MRI	Dm-Post-C_MRI	0.84	< 0.0001	0.82	< 0.0001
	D70-Pre-C_MRI	D70-Post-C_MRI	0.82	< 0.0001	0.81	< 0.0001
	TNR-Pre-C_MRI	TNR-Post-C_MRI	0.48	0.015	0.35	NS