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Fig. 7 | EJNMMI Research

Fig. 7

From: Detection and therapy of neuroblastoma minimal residual disease using [64/67Cu]Cu-SARTATE in a preclinical model of hepatic metastases

Fig. 7

Single-photon emission computed tomography (SPECT) images of 67Cu-SARTATE distribution in mice-bearing intrahepatic NB metastases. Mice were injected with either 9.25 or 18.5 MBq (250 or 500 µCi) of radiolabeled peptide and imaged 24 h post-injection. Imaging anesthesia and instrumentation were as for the PET/CT imaging. A single field of view was used collimated by a multipinhole collimator, with data collected over 30 min (60 s per projection). Representative images of SPECT data in grayscale (top and third row) and SPECT data in color scale fused with CT data (second and bottom row) of mice injected with 9.14 MBq (247 µCi) (low dose, left column) or 18.9 MBq (510 µCi) (high dose, right column) of 67Cu-SARTATE are shown (coronal: top and second row, transaxial: third and bottom row). White arrows on the coronal images show the level of the transaxial slice. Color scale to right, CT for anatomic reference in gray scale

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