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Table 2 Single sample measurements from [99mTc]Tc-PSMA-I&S RGS

From: 99mTc-labelled PSMA ligand for radio-guided surgery in nodal metastatic prostate cancer: proof of principle

 

Weight (g)

 

Tracer uptake in %ID/g

 

SUL (SUV LBM)

 

FFT, n = 92

      

 Mean

0.62

 

0.00022

 

0.16

 

 ± SD

 ± 0.96

 

 ± 0.00064

 

 ± 0.37

 

 Median

0.16

 

0.0

 

0.010

 

 Range

0.01–4.2

 

0.0–0.003

 

0.0–2.0

 
  

p value Mann–Whitney U test

 

p value Mann–Whitney U test

 

p value Mann–Whitney U test

LN samples*, n = 252

 Mean

0.63

 

0.00059

 

0.37

 

 ± SD

 ± 1.1

 

 ± 0.00075

 

 ± 0.40

 

 Median

0.18

 

0.0

 

0.26

 

 Range

0.01–7.8

 

0.0–0.0040

 

0.0–2.2

 

LNM samples*, n = 154

 

 < 0.0001 (LN vs LNM)

 

 < 0.0001 (LN vs LNM)

 

 < 0.0001 (LN vs LNM)

 Mean

0.84

 

0.019

 

12.0

 

 ± SD

 ± 1.2

 

 ± 0.041

 

 ± 24.0

 

 Median

0.36

 

0.0050

 

3.5

 

 Range

0.01–6.0

 

0.0–0.29

 

0.0–169

 
  1. LN lymph node, LNM lymph node metastases, FFT fibro-fatty-tissue, PCa prostate cancer
  2. *60/498 LN-samples containing more than one LN/LNM resulting in overall 356 LN and 171 LNM (including 11 non-nodal PCa tissue)