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Table 1 Patient characteristics and outcome from 6 [99mTc]Tc-PSMA-I&S RGS lymphadenectomies

From: 99mTc-labelled PSMA ligand for radio-guided surgery in nodal metastatic prostate cancer: proof of principle

No

Age at surgery (years)

PSA at surgery (ng/ml)

Gleason score at primary stage

Activity 99mTc-PSMA (MBq)

LN/LNM removed overall (n)

LNM detected (n)

Removed non nodal** PCa-tissue (n)

Anatomical subregions at LA (n)

Manually separated “single-samples” (n)

Number of patients (extended lymph node dissections) overall n = 6

 1

69

2.27

4 + 3

680

79

15

18

78

 2

49

128

5 + 4

660

135

42

1

12

84

 3

63

67.63

4 + 4

692

123

8

15

126

 4

68

0.99

4 + 4

537

36

2

8

56

 5

65

11.78

4 + 4

674

50

8

12

58

 6

52

54.82

4 + 3

584

93

85

10

8

96

 Sum

516

160

11

73

498

Origin of tissue specimens from 73 subregions: n/73 (%)

Right common iliac 7/73 (10%)

Left common iliac 6/73 (8%)

Aortic bifurcation 1/73 (1%)

Right external iliac 6/73 (8%)

Left external iliac 7/73 (10%)

Interaortocaval 3/73 (4%)

Right obturator iliac 4/73 (6%)

Left obturator iliac 4/73 (6%)

Paraaortal 4/73 (5%)

Right internal iliac 7/73 (10%)

Left internal iliac 5/73 (8%)

Miscellaneous* 9/73 (11%)

Right presacral region 6/73 (8%)

Left presacral region 4/73 (5%)

 
  1. LNM lymph node metastases, LN lymph node, PSA prostate specific antigen, LA lymphadenectomy, PCa prostate cancer
  2. *miscellaneous regions: mesorectal, pillar of urinary bladder, region of the musculus piriformis, retroduodenal, renal hilum, ductus deferens
  3. **non-nodal PCa-tissue: residuals of seminal vesicle (n = 7), and deferent duct (n = 3) and solid PCa-tissue in the of left fossa obturatoria (n = 1)