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Fig. 2 | EJNMMI Research

Fig. 2

From: Intraoperative [18F]FDG flexible autoradiography for tumour margin assessment in breast-conserving surgery: a first-in-human multicentre feasibility study

Fig. 2

Workflow of intraoperative FAR imaging. a The LightPath® Imaging System was located within the operating theatre. b Immediately following dissection, the intact WLE specimen was placed in a disposable specimen tray. c The specimen tray and specimen were loaded into the light-tight specimen chamber, and a photographic reference image was acquired to confirm that the specimen was correctly positioned. The specimen contours were drawn on a transparent CRF, and each tumour margin was annotated (not shown). d A 5 μm Mylar separator sheet and a flexible scintillator film were draped over the specimen, and a FAR image was acquired. (e) FAR image of WLE specimen shows elevated tumour radiance. The transparent CRF attached to the LightPath® monitor shows the specimen contours, tumour margin borders, the incision line and the location of the primary tumour (T) in the area of the elevated radiance

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