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Fig. 1 | EJNMMI Research

Fig. 1

From: Intraoperative [18F]FDG flexible autoradiography for tumour margin assessment in breast-conserving surgery: a first-in-human multicentre feasibility study

Fig. 1

Schematic representation of FAR imaging using a flexible scintillating film. Tumour cells containing a PET-radiotracer (e.g. [18F]FDG) emit β+-particles which are converted to scintillations by the flexible scintillator. As β+-particles travel a limited distance in tissue, [18F]FDG containing cells are detected up to approximately 1 mm in tissue. The scintillations are measured by an ultra-sensitive emCCD camera. The flexible scintillators 12 µm thickness makes the scintillator insensitive to 511 keV ɣ-photons

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