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Table 7 Statistical comparison of primary analysis with a consecutive secondary analysis, in which four patients were excluded because of normal PET results that changed the clinical diagnosis from IPS to Non-PS

From: Comparison of 6-[18F]FDOPA PET with Nigrosome 1 detection in patients with parkinsonism

  Primary analysis (43 patients) Secondary analysis (39 patients)
Imaging modality 6-[18F]FDOPA PET N1 (%) 6-[18F]FDOPA PET N1 (%)
Sensitivity 92.6% 81.5 92.6% 81.5
Specificity 93.8% 75.0 91.7% 75.0
Positive predictive value 96.2% 84.6 96.2% 88.0
Negative predictive value 88.2% 70.6 84.6% 64.3
Accuracy 93.0% 79.1 92.3% 79.5
Kappa (all patients) 0.611 (p < 0.001)   0.604 (p < 0.001)