Table 7 Statistical comparison of primary analysis with a consecutive secondary analysis, in which four patients were excluded because of normal PET results that changed the clinical diagnosis from IPS to Non-PS
From: Comparison of 6-[18F]FDOPA PET with Nigrosome 1 detection in patients with parkinsonism
Primary analysis (43 patients) | Secondary analysis (39 patients) | |||
|---|---|---|---|---|
Imaging modality | 6-[18F]FDOPA PET | N1 (%) | 6-[18F]FDOPA PET | N1 (%) |
Sensitivity | 92.6% | 81.5 | 92.6% | 81.5 |
Specificity | 93.8% | 75.0 | 91.7% | 75.0 |
Positive predictive value | 96.2% | 84.6 | 96.2% | 88.0 |
Negative predictive value | 88.2% | 70.6 | 84.6% | 64.3 |
Accuracy | 93.0% | 79.1 | 92.3% | 79.5 |
Kappa (all patients) | 0.611 (p < 0.001) | 0.604 (p < 0.001) | ||