Potential synergy between PSMA uptake and tumour blood flow for prediction of human prostate cancer aggressiveness

EJNMMI Research

Table 4 ROC analysis data for separation of ISUP GG > 2 from GG-1–2 and benign lesions for [⁶⁸Ga]Ga-PSMA-11 SUVmax, ⁸²Rb SUVmax, and the combined model

Measure	Cut-off	AUC	Sensitivity	Specificity	Correctly classified	False negative	False positive	Negative predictive value	Positive predictive value
[⁶⁸Ga]Ga-PSMA-11 SUVmax	18.78	0.84	76%	81%	41	6	5	0.79	0.79
[⁸²Rb]Rb SUVmax	3.90	0.82	80%	78%	41	5	6	0.81	0.77
Combined model	PSMA = 18.78 [⁸²Rb]Rb = 3.90	0.85	96%	74%	44	1	7	0.95	0.77