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Table 2 [68Ga]Ga-PSMA-11 and [82Rb]Rb uptake per ISUP GG including correlations. * Benign lesions are included as ISUP GG = 0

From: Potential synergy between PSMA uptake and tumour blood flow for prediction of human prostate cancer aggressiveness

Tracer Measure Benign
(n = 2)
ISUP Grade Group Correlations
1
(n = 4)
2
(n = 21)
3
(n = 10)
4
(n = 6)
5
(n = 9)
ISUP GG
(n = 50)
ISUP GG*
(n = 52)
[68Ga]Ga-PSMA-11 SUVmax 3.04
[2.5; 3.6]
5.54
[3.7; 26.4]
8.03
[5.1; 36.5]
22.39
[13.8; 80.1]
27.76
[9.3; 41.7]
32.23
[5.5; 61.8]
rho = 0.54
p < 0.001
rho = 0.59
p < 0.001
SUVmean 1.55
[1.3; 1.8]
3.47
[1.7; 10.6]
5.22
[3.5; 12.5]
8.51
[7.0; 22.1]
10.06
[6.4; 14.5]
8.60
[3.1; 18.7]
rho = 0.50
p < 0.001
rho = 0.55
p < 0.001
SUVpeak 1.94
[1.7; 2.2]
2.84
[1.9; 18.3]
4.31
[2.7; 18.9]
10.19
[6.6; 55.4]
14.79
[5.3; 28.7]
12.47
[3.0; 43.7]
rho = 0.51
p < 0.001
rho = 0.56
p < 0.001
[82Rb]Rb SUVmax 1.99
 ± 0.06
3.29
 ± 1.11
3.67
 ± 0.78
4.86
 ± 1.25
4.90
 ± 0.99
4.91
 ± 1.59
rho = 0.50
p < 0.001
rho = 0.56
p < 0.001
SUVmean 1.47
 ± 0.08
2.21
 ± 0.81
2.60
 ± 0.57
2.87
 ± 0.50
3.06
 ± 0.57
2.91
 ± 0.59
rho = 0.35
p = 0.01
rho = 0.42
p = 0.002
SUVpeak 1.63
 ± 0.08
2.78
 ± 0.98
2.90
 ± 0.56
3.73
 ± 0.92
3.94
 ± 0.97
3.80
 ± 0.95
rho = 0.49
p < 0.001
rho = 0.55
p < 0.001