EJNMMI Research

Table 3 Association between PET parameters and therapy response for the 32 patients with head and neck squamous cell carcinoma

From: Interim 4′-[methyl-¹¹C]-thiothymidine PET for predicting the chemoradiotherapeutic response in head and neck squamous cell carcinoma: comparison with [¹⁸F]FDG PET

PET parameter	CR (n = 25)	Non-CR (n = 7)	P value
[¹¹C]4DST
ΔSUVmax	− 66.17 ± 12.66	− 50.25 ± 19.63	0.044
ΔPTV	− 97.11 ± 5.23	− 81.77 ± 14.19	< 0.001
ΔTLP	− 97.88 ± 3.84	− 85.63 ± 13.53	< 0.001
[¹⁸F]FDG
ΔSUVmax	− 49.23 ± 31.35	− 43.85 ± 40.69	0.90
ΔMTV	4.33 ± 107.57	− 34.69 ± 63.19	0.21
ΔTLG	− 10.71 ± 103.99	− 48.70 ± 70.63	0.18

Data are given as mean ± standard deviation
SUVmax, maximum standardized uptake value; PTV, proliferative tumor volume; MTV, metabolic tumor volume; TLP, total lesion proliferation; TLG, total lesion glycolysis; CR, complete response

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