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Table 3 Association between PET parameters and therapy response for the 32 patients with head and neck squamous cell carcinoma

From: Interim 4′-[methyl-11C]-thiothymidine PET for predicting the chemoradiotherapeutic response in head and neck squamous cell carcinoma: comparison with [18F]FDG PET

PET parameter CR (n = 25) Non-CR (n = 7) P value
[11C]4DST    
 ΔSUVmax − 66.17 ± 12.66 − 50.25 ± 19.63 0.044
 ΔPTV − 97.11 ± 5.23 − 81.77 ± 14.19 < 0.001
 ΔTLP − 97.88 ± 3.84 − 85.63 ± 13.53 < 0.001
[18F]FDG    
 ΔSUVmax − 49.23 ± 31.35 − 43.85 ± 40.69 0.90
 ΔMTV 4.33 ± 107.57 − 34.69 ± 63.19 0.21
 ΔTLG − 10.71 ± 103.99 − 48.70 ± 70.63 0.18
  1. Data are given as mean ± standard deviation
  2. SUVmax, maximum standardized uptake value; PTV, proliferative tumor volume; MTV, metabolic tumor volume; TLP, total lesion proliferation; TLG, total lesion glycolysis; CR, complete response