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Table 2 Baseline and interim PET parameters for the 32 patients with head and neck squamous cell carcinoma

From: Interim 4′-[methyl-11C]-thiothymidine PET for predicting the chemoradiotherapeutic response in head and neck squamous cell carcinoma: comparison with [18F]FDG PET

PET parameter

Baseline PET

Interim PET

P value

[11C]4DST

   

 SUVmax

7.01 ± 2.60

2.44 ± 1.05

< 0.001

 PTV

10.52 ± 14.79

0.86 ± 2.10

< 0.001

 TLP

44.34 ± 59.52

2.58 ± 6.42

< 0.001

[18F]FDG

   

 SUVmax

14.80 ± 7.26

6.50 ± 3.32

< 0.001

 MTV

17.49 ± 23.94

11.14 ± 15.27

0.02

 TLG

115.39 ± 178.08

44.92 ± 67.38

0.005

  1. Data are given as mean ± standard deviation
  2. SUVmax, maximum standardized uptake value; PTV, proliferative tumor volume; MTV, metabolic tumor volume; TLP, total lesion proliferation; TLG, total lesion glycolysis