Fig. 3
Case 002. Panel A, transaxial fused [18F]FDG PET/CT image of the liver and MIP image demonstrating FDG-avid liver, peritoneal and nodal metastases as well as a synchronous left sided carotid paraganglioma (small arrow). Panel B, [68 Ga]Ga-DOTATATE PET/CT MIP image, demonstrating that few liver metastases show uptake higher than background liver (SUVmax 13, large arrow, vs 6.5 for background liver). It should be noted that not all liver lesions were biopsied so it remains unclear if all liver lesions were metastatic wtGIST deposits or if the carotid paraganglioma was also metastatic to the liver. The left sided carotid paraganglioma shows very intense uptake of the somatostatin analogue (SUVmax 60, small arrow). Panel C, negative SSTR2 expression on IHC in a biopsied dSDH wtGIST liver metastasis from case 002