Skip to main content

Table 2 Total distribution volume (VT) of brain regions after injection of [18F]LSN3316612

From: PET quantification of brain O-GlcNAcase with [18F]LSN3316612 in healthy human volunteers

RegionVT (mL·cm−3)a
MeanCOV (%)
Amygdala17.628.3
Hippocampus15.524.6
Cingulate14.525.2
Insula14.424.0
Temporal13.924.2
Frontal12.923.8
Striatum12.723.7
Parietal12.222.2
Occipital11.621.6
Globus pallidus11.525.0
Cerebellum11.322.3
Thalamus11.222.8
White matter (WM)10.326.2
Cerebellar WM9.123.7
Corpus callosum8.036.8
Brainstem7.924.5
Mean12.224.9
  1. COV coefficient of variation
  2. aVT was calculated using a two-tissue compartment model. Values represent the mean and coefficient of variation (COV = mean/SD) from the baseline scans of 17 healthy volunteers