Table 1 Demographic characteristics and PET scan parameters for 17 healthy volunteers injected with [18F]LSN3316612
From: PET quantification of brain O-GlcNAcase with [18F]LSN3316612 in healthy human volunteers
Volunteer demographics and PET scan parameters | Kinetic evaluation (n = 17) | Test-retest study (n = 10) | Radiation dosimetry (n = 6) | |
|---|---|---|---|---|
Baseline brain | Test | Retest | Whole body | |
Male:female (n) | 8:9 | 5:5 | 5:5 | 3:3 |
Age (years) | 40 ± 11 | 43 ± 11 | 43 ± 11 | 34 ± 16 |
Body weight (kg) | 73 ± 17 | 72 ± 16 | 75 ± 17 | 69 ± 12 |
Injected activity (MBq) | 187 ± 6 | 185 ± 7 | 189 ± 3 | 172 ± 47 |
Molar activity (MBq/nmol) | 55 ± 22 | 45 ± 16 | 50 ± 13 | 64 ± 9 |
Injected mass dose (nmol/kg) | 0.058 ± 0.033 | 0.069 ± 0.038 | 0.057 ± 0.016 | 0.040 ± 0.011 |