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EJNMMI Research

Table 2 UM-SCC-74B spheroid growth ratio-development over time in mean and SD. n ≥ 4

From: Enhancing the therapeutic effects of in vitro targeted radionuclide therapy of 3D multicellular tumor spheroids using the novel stapled MDM2/X-p53 antagonist PM2

 

Untreated

100 kBq 177Lu-rituximab

PM2 [20 μM]

30 kBq 177Lu-AbN44v6

100 kBq 177Lu-AbN44v6

30 kBq 177Lu-AbN44v6 & PM2

100 kBq 177Lu-AbN44v6 & PM2

Day

Mean

SD

Mean

SD

Mean

SD

Mean

SD

Mean

SD

Mean

SD

Mean

SD

3

3.81

0.37

2.30

0.57

1.53

0.23

2.73

0.43

2.19

0.57

1.48

0.25

1.45

0.30

6

9.87

0.71

5.32

1.52

3.4

0.43

6.69

1.49

3.6

1.07

1.95

0.43

1.59

0.38

10

21.01

2.63

16.57

1.67

14.98

2.15

15.4

2.79

13.12

4.21

5.43

2.09

1.44

0.63

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