Fig. 7

In vivo behavior of [¹¹¹In]In-pb12 in MCF-7 xenograft mice. a Representative SPECT/CT coronal image at 12 min post-injection showing major elimination of [¹¹¹In]In-pb12 by the liver and minor elimination by the bladder. b Representative SPECT/CT sagittal image at 12 min post-injection showing major elimination of [¹¹¹In]In-pb12 by the liver. c Tumor/muscle ratio at 12 min post-injection of [¹¹¹In]In-pb12 in MCF-7 xenografted mice determined on the SPECT/CT images. Co-injection of non-labeled pb12 (blocked group) significantly decreases the tumor/muscle ratio. L stands for liver, B means bladder and T stands for MCF-7 tumor