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Fig. 4. | EJNMMI Research

Fig. 4.

From: Design, synthesis, and biological evaluation of a multifunctional neuropeptide-Y conjugate for selective nuclear delivery of radiolanthanides

Fig. 4.

a NPY receptor activation profile by measurement of IP accumulation upon stimulation of the hY1R and hY2R with NPY conjugates NPY, [F7,P34]-NPY, pb12, [natTb]Tb-pb12, and [natTb]Tb-pb13. b Receptor internalization studies on HEK293 cells stably expressing the hY1R or hY2R fused to eYFP (green) following stimulation with [natTb]Tb-pb12 and pb13. Scale bar = 10 μm

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