Spinal cord hypermetabolism extends to skeletal muscle in amyotrophic lateral sclerosis: a computational approach to [18F]-fluorodeoxyglucose PET/CT images

EJNMMI Research

Table 2 Predictive power of tested variables at univariate and multivariate analysis

Variable	Outcome results			Univariate analysis			Cox regression model
	No. of patients	No. of deaths	Mortality rate (%)	Hazard ratio	95% confidence interval	p	Hazard ratio	95% confidence interval	p
Age
< 63 years	28	7	25	1 (reference)	–	0.1
> 63 years	28	14	50	2.37	0.771–7.32	0.1
Psoas volume
< 3.4	28	13	46	1 (reference)	–	0.17
> 3.4	28	8	29	2.17	0.717–6.550	0.17
Psoas N-SUV
< 0.42	28	9	32	1 (reference)	–	0.41
> 0.42	28	12	43	1.58	0.53–4.71	0.41
BA4 SUV
< 5.48	28	14	50	3.38	1.09–10.55	0.03
> 5.48	28	7	25	1 (reference)	–	0.03
ALSF score
< 40	28	10	36	1 (reference)	–	0.57
> 40	28	11	39	1.36	0.46–4.06	0.57
Psoas CV-SUV
< 6.59%	28	6	21	1 (reference)	–	0.016
> 6.59%	28	15	54	4.23	1.31–13.62	0.016
Spinal cord N-SUV
< 0.92	28	4	14%	1 (reference)	–	0.001	1 (reference)	–	0.001
> 0.92	28	17	61	9.27	2.5–34.1	0.001	5.17	1.74–15.38	0.001