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Table 2 68Ga-ABY-025 SUVs and parametric image values in normal liver and liver metastasis, median (range)

From: Kinetic analysis of HER2-binding ABY-025 Affibody molecule using dynamic PET in patients with metastatic breast cancer

 

SUV 2 h

SUV 4 h

2TC-3k K1

2TC-3k Ki

Patlak Ki

Normal liver

4.9 (3–6.7)

4.8 (3.8–6.1)

0.37 (0.20–0.56)

0.015 (0.006–0.03)

0.008 (0.004–0.016)

All liver met

10 (3.1–32.4)

10 (3.6–39)

0.20 (0.02–0.38)

0.025 (0.009–0.095)

0.025 (0.003–0.094)

p value*

< 0.0001

0.008

0.0001

0.019

0.0002

  1. SUV standardized uptake value, 2TC-3k irreversible two-tissue compartment model, Ki transfer rate constant
  2. *Mann-Whitney-Wilcoxon test