Table 1 Patient characteristics, history of prostate cancer and outcome from lymphadenectomies from 23 patients undergoing lymphadenectomy
Parameters | Values |
|---|---|
iPSA at primary therapy (ng/ml) | |
Mean ± SD/median/range | 10.79 ± 7.5/8.8/3.37–37.0 |
Primary therapy, n | |
Radical prostatectomy | 21/23 (91.3%) |
Radiotherapy | 2/23 (8.7%) |
Gleason score, n | |
7a | 4 (17%) |
7b | 7 (31%) |
8 | 5 (22%) |
9 | 7 (30%) |
111In-PSMA-guided LA overall, n | |
Primary | 2/23 (8.7%) |
Salvage lymph node dissection | 21/23 (91.3%) |
Age at lymphadenectomy (years) | |
Mean ± SD/median/range | 67.5 ± 6.6/67/52–78 |
PSA at 111In-PSMA-guided LA (ng/ml) | |
Mean ± SD/median/range | 7.9 ± 12.9/1.8/0.03–56.2 |
Time between PET/CT and 111In-PSMA-guided LA (months) | |
Mean ± SD/median/range | 3.2 ± 1.6/3.0/1.0–8.0 |
Time between primary therapy and 111In-PSMA-guided LA (years) (n = 21) | |
Mean ± SD/median/range | 4.9 ± 3.7/4.4/1.5–13.7 |
Histological outcome for 23 patients, n | |
LA with positive histology | 21/23 (91.3%) |
LA with negative histology | 2/23 (8.7%) |
Topography of 111In-PSMA-guided LA in 23 patients, n | |
Pelvic right and left | 13/23 (57%) |
Pelvic left only | 2/23 (9%) |
Pelvic right only | 1/23 (4%) |
Pelvic right and left and retroperitoneal | 7/23 (30%) |
Topography of subregions with confirmed PCa, n | |
Pelvic left, n | 38/275 (37%) |
Pelvic right, n | 41/275 (40%) |
Retroperitoneal | 24/275 (23%) |
Histological outcome for 275 subregions with 275 samples, n | |
Subregions/samples with LNM | 104/275 (37.5%) |
Subregions/samples without LNM | 171/275 (62.5%) |
Subregions/samples with additional non-nodal PCa-tissue | 7/104 (5.8%) |
Number of LN removed (n) | |
Overall | 864 |
Per patient (mean ± SD/median/range) | 37.6 ± 17.2/38.0/2.0–82.0 |
Number of LNM removed (n) | |
Overall | 197 |
Per patient (mean ± SD/median/range) | 8.6 ± 14.9/4.0/0.0–71.0 |
LNM fraction per patient (LNM×100/LN = %) | |
Mean ± SD/median/range | 20.9 ± 24.4/12.5/0.0–87.1 |