Disease activity and response to therapy monitored by [18F]FDG PET/CT using volume-based indices in IgG4-related disease

EJNMMI Research

Table 2 Correlation of [¹⁸F]FDG PET indices before therapy with serum inflammatory biomarkers in patients with IgG4-RD

[¹⁸F]FDG PET	Serum inflammatory biomarkers
	IgG4 (n = 17)		sIL-2R (n = 13)
	ρ	P	ρ	P
Number of involved organs	0.490	0.046	0.873	< 0.001
SUVmax	0.455	0.067	0.467	0.108
Total MTV	0.879	< 0.001	0.599	0.031
Total TLG	0.873	< 0.001	0.599	0.031

sIL-2R = soluble IL-2 receptor, SUVmax = maximum standardized uptake value, MTV = metabolic tumor volume, TLG = total lesion glycolysis