Table 1 Numbers of subjects in each dose group and PET scan time points after oral dosing with the α2C-adrenoceptor antagonist ORM-12741
Dose (mg) | No. of subjects scanned at baseline | No. of subjects scanned at 1 h | No. of subjects scanned at 3.5 h | No. of subjects scanned at 6 h | No. of subjects scanned at 6.5 h | No. of subjects scanned at 12 h |
|---|---|---|---|---|---|---|
0.3 | 2 | 1 | 1 | 1 | 1 | |
1 | 3a | 1 | 1 | 1 | 1 | |
10 | 5 | 3 | 3 | 2 | 2 | |
30 | 5 | 3 | 3 | 2 | 2 | |
60 | 4 | 4 | 4 | 4 |