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Fig. 2 | EJNMMI Research

Fig. 2

From: [18F]-Fluciclovine PET discrimination of recurrent intracranial metastatic disease from radiation necrosis

Fig. 2

A 43-year-old patient with metastatic colon cancer with prior stereotactic radiosurgery with follow-up MRI demonstrating multiple enhancing brain lesions suspicious for recurrent disease. Top panel demonstrating a right cerebellar lesion (green arrow) with low fluciclovine uptake (SUVmax of 1.2) on transaxial PET (a) and corresponding focal FLAIR hyperintensity (b) T1 + contrast (c) and fused FLAIR and PET (d). This lesion did not increase in size on follow-up MRI and was consistent with radiation necrosis. A left occipital lesion (green arrow) in the same patient had high fluciclovine uptake (SUVmax of 2.5) on transaxial PET (e), hyperintense FLAIR (f), T1 + contrast enhancement (g), and fused FLAIR and PET (h). The left occipital lesion was found to be recurrent metastatic disease upon resection

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