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Table 4 (a) Mean and standard deviation (n = 40 dosimetry analyses) of OAR organ masses, TIACs and ADs calculated using Dosimetry Toolkit + OLINDA/EXM® V1.0 and PLANET® Dose with LDM and DK and density correction. (b) Relative differences (%) of the organ mass values and TIACs between PLANET® Dose and Dosimetry Toolkit + OLINDA, DTK, Dosimetry Toolkit

From: Clinical implementation of PLANET® Dose for dosimetric assessment after [177Lu]Lu-DOTA-TATE: comparison with Dosimetry Toolkit® and OLINDA/EXM® V1.0

(a)

ORGANS

Mass (g)

TIAC (h)

Absorbed dose (Gy)

DTK + OLINDA/EXM® V1.0

PLANET®Dose

DTK + OLINDA/EXM® V1.0

PLANET® Dose

DTK + OLINDA/EXM® V1.0

PLANET®Dose

LDM

DK

Liver

2141.6 ± 1213.3

2191.7 ± 1205

14.9 ± 24.1

15.1 ± 24.2

3.40 ± 3.9

3.27 ± 3.7

3.21 ± 3.6

Kidneys

478.3 ± 111.4

461.5 ± 108.3

2.2 ± 0.7

2.4 ± 0.8

3.01 ± 0.9

3.23 ± 0.9

3.16 ± 0.9

Spleen

290.4 ± 181.3

281.7 ± 178.5

2.0 ± 1.5

2.0 ± 1.4

4.15 ± 1

4.45 ± 1.2

4.36 ± 1.2

(b)

Relative difference (%)/DTK+OLINDA

 

Mass

TIAC

Liver

Kidneys

Spleen

Liver

Kidneys

Spleen

Mean

2.9

−3.4

−2.4

5.7

6.4

4.9

Min

−4.0

−18.8

−23.4

−6.9

−9.1

−18.9

Max

19.7

16.4

17.3

17.3

25.7

23.5

RMSD

5.2

7.2

8.9

8.1

9.4

10.4