Striatal dopamine transporter SPECT quantification: head-to-head comparison between two three-dimensional automatic tools

EJNMMI Research

Table 1 (a) Correlation between Datquant® and BasGanV2 SBR, ratio, and asymmetries and (b) correlation between MDS-UPDRS-III score and SBR, ratio, asymmetries achieved with Datquant® and BasGanV2

	Right caudate	Left caudate	Right putamen	Left putamen	Right P/C ratio	Left P/C ratio	Caudate asymmetry	Putamen asymmetry
(a)
Datquant®/ BasGan V2	r = .771 p < .0001*	r = .752 p < .0001*	r = .866 p < .0001*	r = .847 p < .0001*	r = .793 p < .0001*	r = .706 p < .0001*	r = .887 p < .0001*	r = .783 p < .0001*
(b)
Datquant® /UPDRS-III	− .414 p = .0015*	− .434 p = .0009*	− .251 p = .0405	− .282 p = .0248	.027 p = .4275	.095 p = .2573	.423 p = .0012*	.201 p = .0413
BasGan V2 /UPDRS-III	− .523 p = .0001*	− .532 p = .0001*	− .366 p = .0048*	− .447 p = .0006*	− .361 p = .0053*	.082 p = .2884	.277 p = .0268	.321 p = .0122

In the columns, the values of SBR, P/C ratio, and asymmetry are reported. Asymmetries are computed without taking into account the side of the more affected hemisphere. See the text for abbreviations. Italics characters show statistically significant correlation (one-tail Pearson’s r), while * denotes those correlations surviving Bonferroni’s correction for multiple comparisons (p = .00625 as first level of statistical significance)