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Table 4 Relative differences to the reference algorithm: smoothed data

From: Asphericity of tumor FDG uptake in non-small cell lung cancer: reproducibility and implications for harmonization in multicenter studies

 

Relative differences, % (median, IQR)

p value

Smoothed to 7 mm versus 7 mm

Original 7 mm versus 7 mm

ASP

 TOF4/8

13.9 (9.3–32.8)

7.6 (3.1–18.0)

0.001

 TOF4/16

9.1 (4.9–26.2)

–

–

 PSF + TOF2/17

17.7 (5.2–37.6)

12.8 (6.3–26.9)

0.9

 Q.Clear

17.6 (5.9–37.2)

31.3 (11.2–43.7)

< 0.001

SUVmax

 TOF4/8

1.6 (0.7–2.9)

1.2 (0.6–2.0)

0.08

 TOF4/16

1.9 (1.0–3.3)

–

–

 PSF + TOF2/17

8.9 (4.4–12.6)

4.9 (1.9–7.2)

< 0.001

 Q.Clear

4.8 (1.8–6.6)

5.1 (2.4–10.6)

0.021

MTV

 TOF4/8

3.2 (1.5–5.8)

2.3 (1.4–4.4)

0.18

 TOF4/16

3.1 (1.2–4.8)

–

–

 PSF + TOF2/17

10.6 (5.4–16.5)

6.1 (3.1–12.7)

< 0.001

 Q.Clear

6.2 (3.4–9.8)

6.3 (3.1–13.2)

0.003

  1. Relative differences in % (with interquartile range; IQR) are given for each algorithm relative to the reference algorithm TOF4/16 at 7 mm FWHM (i.e., TOF4/16/6.4). Differences are displayed separately for either the retrospectively smoothed data (5 mm smoothed to 7 mm FWHM) or original 7 mm data. Missing values reflect pairs of identical datasets. Significant p values are printed in bold