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EJNMMI Research
Fig. 4 | EJNMMI Research

Fig. 4

From: Asphericity of tumor FDG uptake in non-small cell lung cancer: reproducibility and implications for harmonization in multicenter studies

Fig. 4

Correlation plots for ASP and MTV. Correlation plots for ASP and MTV for the three TOF4/16 algorithms. a shows plots for all patients. Correlation was moderate with TOF4/16/2 and moderate to high with TOF4/16/6.4 and TOF4/16/9.5. b Correlation was negligible (r < 0.3) in lesions with MTV ≤ 15 ml for TOF4/16/2, while the threshold was lower for TOF4/16/6.4 (MTV ≤ 2.5 ml) and TOF4/16/9.5 (MTV ≤ 5.0 ml). The generally lower correlation of ASP and MTV in smaller lesions results from the limited spatial resolution. With TOF4/16/2, high noise level contributes to the high MTV threshold for correlation. With TOF4/16/9.5, the poorer reconstructed spatial resolution may contribute to the higher MTV threshold compared to TOF4/16/6.4

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