Fig. 2

The metabolic connection network of HC2 subjects (a), PD2 patients at baseline (b), PD2 patients at 3-month post-operation (c), PD2 patients at 12-month post-operation (d) in PDRP subspaces at a sparsity threshold of 25%. The blue circle nodes indicate different anatomical brain regions. Red and green lines indicate pathological (i.e., significantly altered, P-value with FDR correlated < 0.05) and normal metabolic connection between brain regions of PDRP subspaces