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Table 2 Metastatic disease locations and median lesion SUVmax for each patient

From: Gallium-68 prostate-specific membrane antigen ([68Ga]Ga-PSMA-11) PET for imaging of thyroid cancer: a feasibility study

Patient #

Tumor type

Disease locations

PSMA median SUVmax (range)

FDG median SUVmax (range)

Neck MRI findings

Liver SUVmax

PSMA > liver + No FDG/PSMA discordance?

1

PTC

B

9.0 (1.0–10.1)

21.1 (4.1–28.4)

Post-tx, bone mets (P,F)

7.2

Yes

2

HCC

B, ST

11.0 (3.4–27.8)

11.6 (4.7–31.3)

Post-tx, bone mets (F)

13.2

Yes

3

PDPTC

ST

4.5 (1.9–6.2)

5.3 (4.1–10.3)

Post-tx (non-avid)

5.6

Yes

4

ATC

ST, TB

3.3 (1.6–6.0)

14.3 (4.2–19.1)

Post-tx, “treated” residual TB tissue (P,F)

9.5

No

5

FTC

B

15.0 (15.0–15.0)

3.5 (3.5–3.5)

Post-tx (non-avid)

6.5

Yes

6

PDPTC

LN, ST, TB

8.5 (4.3–12.6)

4.1 (2.6–5.6)

Post-tx (P,F)

10.2

Yes

7

PTC

ST

2.7 (2.7–2.7)

17.0 (17.0–17.0)

Post-tx (non-avid)

9.2

No

8

ATC

TB

6.0 (5.7–6.3)

14.1 (13.8–14.3)

Post-tx, TB soft tissue (P,F)

5.7

Yes

9

PTC

LN

2.5 (2.0–11.4)

5.9 (5.3–6.9)

Post-tx, decreasing cervical LN (F)

7.1

Yes

10

FTC

B

13.8 (9.2–18.3)

8.0 (7.4–8.7)

Post-tx (non-avid)

5.4

Yes

11

HCC

ST

2.8 (2.5–3.1)

4.3 (3.9–4.7)

Post-tx (non-avid)

13.9

No

  1. B bones, ST soft tissues, TB thyroid bed, LN lymph nodes, Post-tx post-treatment changes (thyroidectomy, scarring, and/or lymph node dissection). The last column refers to PSMA RLT eligibility criteria used in a recent phase 2 trial of PSMA RLT in prostate cancer [21]. Reasons for lack of eligibility: patient 4—FDG avid lung metastases not seen on PSMA; patient 8—FDG avid lung metastases with minimal uptake on PSMA; patient 12—FDG avid lung metastases not seen on PSMA