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Table 5 Correlation coefficients between cortical glutamate levels and baseline [18F]FDG PET results (SUVpre) with Fisher’s Z-transformation

From: In vivo glucose metabolism and glutamate levels in mGluR5 knockout mice: a multimodal neuroimaging study using [18F]FDG microPET and MRS

MRS region PET region mGluR5 KO WT Fisher’s Z p value
n Rho p value n Rho p value
PFC CTX 9 − 0.83 0.005** 10 0.08 0.829 − 2.30 0.022*
HIP 9 − 0.75 0.020* 10 0.02 0.960 − 1.78 0.075
THA 9 − 0.68 0.042* 10 − 0.03 0.934 − 1.45 0.148
STR 9 − 0.90 0.001*** 10 0.07 0.855 − 2.77 0.006**
CB 9 − 0.73 0.025* 10 0.05 0.881 − 1.78 0.075
WB 9 − 0.82 0.007** 10 − 0.03 0.934 − 2.01 0.045*
HIP CTX 10 0.09 0.803 10 0.09 0.803 0.00 1.000
HIP 10 0.19 0.603 10 0.18 0.627 0.02 0.982
THA 10 0.05 0.881 10 0.24 0.511 − 0.35 0.729
STR 10 0.27 0.446 10 0.04 0.907 0.45 0.656
CB 10 0.13 0.726 10 0.15 0.676 − 0.05 0.962
WB 10 0.03 0.934 10 0.24 0.511 − 0.51 0.613
  1. SUV standardized uptake value, KO knockout, WT wild type, PFC prefrontal cortex, CTX cortex, HIP hippocampus, THA thalamus, STR striatum, CB cerebellum, WB whole brain
  2. *p < 0.05, **p < 0.01, ***p < 0.001