In vivo glucose metabolism and glutamate levels in mGluR5 knockout mice: a multimodal neuroimaging study using [18F]FDG microPET and MRS

EJNMMI Research

Table 1 Demographic characteristics and scan parameters

Variables	Mouse type		t-value	p-value
Variables	mGluR5 KO (n = 11) Mean ± SD	WT (n = 10) Mean ± SD	t-value	p-value
Age (day)	252.6 ± 68.5	222.4 ± 45.9	1.66	0.10
Male/female	8/3	5/5	0.39^†	0.39
Weight (g)	22.9 ± 4.2	24.0 ± 3.5	− 0.93	0.36
[¹⁸F] FDG injected dose (MBq)	4.1 ± 0.6	4.3 ± 0.6	− 1.02	0.32
[¹⁸F] FDG injected dose/weight (MBq/g)	0.18 ± 0.37	0.18 ± 0.32	0.20	0.84