Table 4 [18F]FDG PET parameters and response to neoadjuvant CTX. ΔMTV parameter was significantly associated with pathological response to Neo-CTX (Mann–Whitney test). IQR: interquartile range
Tissue Response to Neo-CTX ≤ 90% | Tissue Response to Neo-CTX > 90% | p value | |||||
|---|---|---|---|---|---|---|---|
IQR 25 | Median | IQR 75 | IQR 25 | Median | IQR 75 | ||
PET1-SUVmax | 6.0 | 8.4 | 10.6 | 5.1 | 7.9 | 11.2 | 0.949 |
PET1-SUVmean | 2.4 | 4.0 | 4.8 | 2.9 | 4.5 | 5.1 | 0.652 |
PET1-SUVpeak | 3.8 | 6.7 | 7.5 | 4.0 | 5.5 | 6.9 | 0.813 |
PET1-MTV | 41.1 | 171.4 | 261.3 | 102.7 | 139.5 | 336.7 | 0.377 |
PET1-TLG | 15.9 | 108.1 | 259.9 | 72.0 | 112.4 | 302.0 | 0.377 |
PET2-SUVmax | 2.7 | 3.4 | 5.2 | 2.2 | 2.9 | 3.4 | 0.201 |
PET2-SUVmean | 1.8 | 2.1 | 3.0 | 1.4 | 1.8 | 2.2 | 0.146 |
PET2-SUVpeak | 2.3 | 2.8 | 4.5 | 1.8 | 1.9 | 2.9 | 0.146 |
PET2-MTV | 54.7 | 101.7 | 176.1 | 34.8 | 67.2 | 103.4 | 0.310 |
PET2-TLG | 31.7 | 44.3 | 172.1 | 19.4 | 46.1 | 80.6 | 0.683 |
Δ SUVmax | − 64% | − 57% | − 11% | − 85% | − 59% | − 36% | 0.377 |
Δ SUVmean | − 51% | − 34% | − 3% | − 69% | − 50% | − 38% | 0.102 |
Δ SUVpeak | − 62% | − 46% | − 11% | − 74% | − 58% | − 40% | 0.234 |
Δ MTV | − 52% | − 34% | − 14% | − 87% | − 59% | − 35% | 0.037 |
Δ TLG | − 60% | − 50% | − 22% | − 94% | − 63% | − 45% | 0.051 |