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Fig. 2 | EJNMMI Research

Fig. 2

From: Brain SPECT perfusion and PET metabolism as discordant biomarkers in major depressive disorder

Fig. 2

Scatter plot of Spearman’s correlations on extracted clusters. The increased number of depressive episodes is correlated with decreased perfusion of: a the right insula (rho = − 0.58, p = 0.01), b the right anterior cingulate cortex (ACC) (rho = − 0.49, p = 0.02), c the left precuneus (rho = − 0.50, p = 0.02), d the right medial temporal cortex (rho = − 0.84, p = 0.00002) and e the right middle frontal cortex (rho = − 0.49, p = 0.02). This correlation is not significant with the metabolism of: a the right insula (rho = − 0.23, p = 0.40), b the right ACC (rho = − 0.21, p = 0.20), c the left precuneus (rho = 0.20, p = 0.77), d the right medial temporal cortex (rho = − 0.23, p = 0.20) and e the right middle frontal cortex (rho = 0.16, p = 0.55). f The increased depression duration is correlated with decreased perfusion of the right ACC (rho = − 0.61, p = 0.01). This correlation is not significant with the metabolism of the right ACC (rho = 0.08, p = 0.76)

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