Fig. 5

Representative immunohistochemical images (original magnification × 400) of AT8 (a, b, arrows) and GFAP (c, d) stained brain sections of each 55 weeks old wild type (wt; a, c) and Apolipoprotein E-deficient (ApoE−/−; b, d) mouse as well as the quantitative analysis of cortical GFAP-positive cells (e, n = 8 of each mouse strains) given as number per high power field (HPF). Values are given as means ± SD. Unpaired Student-t test followed by Mann–Whitney Rank sum test: *p < 0.05 versus wt