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Fig. 4 | EJNMMI Research

Fig. 4

From: Longitudinal [18F]FDG-PET/CT analysis of the glucose metabolism in ApoE-deficient mice

Fig. 4

Target-to-brain stem ratio of [18F]FDG uptake in the cortex (SUVRCTX/BS), hippocampus (SUVRHIP/BS), thalamus (SUVRTH/BS), striatum (SUVRST/BS), and cerebellum (SUVRCB/BS) of wild type (wt; n = 8) and Apolipoprotein E-deficient (ApoE−/−; n = 8) mice (ae). Values are given as mean ± SD; ANOVA for repeated measurements followed by Holm-Sidak comparison test: *p < 0.05 versus wt, #p < 0.05 versus 15 weeks. Visual comparison of [18F]FDG uptake in the brain of wt (fh) and ApoE−/− mice (ik). Transversal (f, i), sagittal (g, j), and coronal (h, k) [18F]FDG-PET/CT and MRI with M. Mirrione VOI template overlay and fusion (template: cortex—blue, striatum—red, thalamus—light green, hippocampus—dark green, cerebellum—yellow, brain stem—brown)

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