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Table 1 αvβ8-Integrin affinities (expressed as 50% inhibition concentrations, IC50) and n-octanol-PBS distribution coefficients (log D7.4). Affinities were determined using the non-radioactive 69/71GaIII complexes, where applicable

From: Tracking a TGF-β activator in vivo: sensitive PET imaging of αvβ8-integrin with the Ga-68-labeled cyclic RGD octapeptide trimer Ga-68-Triveoctin

Compound IC50 (95% confidence interval) [nm] log D7.4
68Ga-Triveoctin (trimer) 5.7 (3.6–9.0) − 3.1 ± 0.1
68Ga-TRAP-AvB8 (monomer) 38 (25–58) − 3.9 ± 0.1
AvB8-pentynoic amide 17 (12–24) n/a