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Fig. 6 | EJNMMI Research

Fig. 6

From: Tracking a TGF-β activator in vivo: sensitive PET imaging of αvβ8-integrin with the Ga-68-labeled cyclic RGD octapeptide trimer Ga-68-Triveoctin

Fig. 6

Representative PET images (maximum intensity projections, 60 min p.i., OSEM3D reconstruction) of a SCID mouse bearing a subcutaneous MeWo xenograft (human melanoma, positions indicated by white arrow), using 68Ga-TRAP-AvB8 (a 12 MBq, 35 pmol, 350 MBq/nmol) and 68Ga-Triveoctin (b 9 MBq, 25 pmol, 350 MBq/nmol). Blockade (c) was done by administration of 60 nmol Triveoctin, 10 min prior to the radiopharmaceutical. Purple and green arrows indicate presence of activity in kidneys and urinary bladder, respectively

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