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Table 3 Kinetic parameters, determined using compartment analysis

From: Quantitative evaluation of hepatic integrin αvβ3 expression by positron emission tomography imaging using 18F-FPP-RGD2 in rats with non-alcoholic steatohepatitis

Group Model K1 k2 k3 k4 AIC
3–4 weeks
Normal diet 1T2CM 1.06 ± 0.26 2.08 ± 0.40 89.33 ± 4.8
2T3CM 1.43 ± 0.34 3.63 ± 0.87 0.05 ± 0.012 0.03 ± 0.0063 35.96 ± 3.8
CDHFD 1T2CM 0.74 ± 0.14 1.15 ± 0.32 93.31 ± 10.7
2T3CM 0.90 ± 0.12 1.94 ± 0.47 0.05 ± 0.020 0.02 ± 0.0021 41.14 ± 3.9
9–10 weeks
Normal diet 1T2CM 0.87 ± 0.34 1.56 ± 0.85 97.59 ± 3.8
2T3CM 1.26 ± 0.14 3.00 ± 0.40 0.05 ± 0.0075 0.02 ± 0.0048 43.93 ± 5.9
CDHFD 1T2CM 0.42 ± 0.26 0.51 ± 0.61 100.3 ± 7.9
2T3CM 0.69 ± 0.14 1.19 ± 0.39 0.07 ± 0.0079 0.02 ± 0.0029 32.12 ± 7.8
  1. Values are expressed as means ± SDs (n = 5)
  2. CDHFD choline-deficient, low-methionine high-fat diet, 1T2CM one-tissue two-compartment model, 2T3CM two-tissue three-compartment model, AIC Akaike information criterion