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Table 1 Tissue distribution of [11C]4 in male ddY mice

From: Synthesis and evaluation of N-isopropyl-p-[11C]methylamphetamine as a novel cerebral blood flow tracer for positron emission tomography

Tissue Time after injection (min)
1 5 15 30 60
Blood 0.27 ± 0.04 0.26 ± 0.03 0.32 ± 0.05 0.23 ± 0.03 0.13 ± 0.02
Heart 1.91 ± 0.14 0.91 ± 0.07 0.54 ± 0.02 0.36 ± 0.04 0.18 ± 0.03
Lung 12.61 ± 1.18 6.10 ± 0.88 2.85 ± 0.39 1.24 ± 0.20 0.67 ± 0.05
Liver 0.43 ± 0.12 1.39 ± 0.25 1.77 ± 0.24 1.24 ± 0.05 0.81 ± 0.03
Pancreas 1.32 ± 0.23 2.49 ± 0.19 2.39 ± 0.33 1.30 ± 0.15 0.62 ± 0.30
Spleen 0.92 ± 0.12 1.52 ± 0.32 1.32 ± 0.11 0.66 ± 0.08 0.33 ± 0.07
Small intestine 1.29 ± 0.14 1.51 ± 0.15 1.32 ± 0.25 0.68 ± 0.06 0.35 ± 0.08
Kidney 4.28 ± 1.05 4.70 ± 0.38 2.69 ± 0.61 1.64 ± 0.20 0.98 ± 0.09
Muscle 0.63 ± 0.11 0.69 ± 0.08 0.44 ± 0.05 0.27 ± 0.04 0.21 ± 0.08
Brain 1.13 ± 0.23 1.69 ± 0.12 1.44 ± 0.11 0.75 ± 0.12 0.34 ± 0.04
Brain/blood 4.16 ± 0.60 6.54 ± 0.50 4.51 ± 0.52 3.29 ± 0.37 2.61 ± 0.52
  1. The radioactivity levels are expressed as SUVs
  2. Data represent the mean ± SD (n = 4)