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Table 1 Tissue distribution of [11C]4 in male ddY mice

From: Synthesis and evaluation of N-isopropyl-p-[11C]methylamphetamine as a novel cerebral blood flow tracer for positron emission tomography

Tissue

Time after injection (min)

1

5

15

30

60

Blood

0.27 ± 0.04

0.26 ± 0.03

0.32 ± 0.05

0.23 ± 0.03

0.13 ± 0.02

Heart

1.91 ± 0.14

0.91 ± 0.07

0.54 ± 0.02

0.36 ± 0.04

0.18 ± 0.03

Lung

12.61 ± 1.18

6.10 ± 0.88

2.85 ± 0.39

1.24 ± 0.20

0.67 ± 0.05

Liver

0.43 ± 0.12

1.39 ± 0.25

1.77 ± 0.24

1.24 ± 0.05

0.81 ± 0.03

Pancreas

1.32 ± 0.23

2.49 ± 0.19

2.39 ± 0.33

1.30 ± 0.15

0.62 ± 0.30

Spleen

0.92 ± 0.12

1.52 ± 0.32

1.32 ± 0.11

0.66 ± 0.08

0.33 ± 0.07

Small intestine

1.29 ± 0.14

1.51 ± 0.15

1.32 ± 0.25

0.68 ± 0.06

0.35 ± 0.08

Kidney

4.28 ± 1.05

4.70 ± 0.38

2.69 ± 0.61

1.64 ± 0.20

0.98 ± 0.09

Muscle

0.63 ± 0.11

0.69 ± 0.08

0.44 ± 0.05

0.27 ± 0.04

0.21 ± 0.08

Brain

1.13 ± 0.23

1.69 ± 0.12

1.44 ± 0.11

0.75 ± 0.12

0.34 ± 0.04

Brain/blood

4.16 ± 0.60

6.54 ± 0.50

4.51 ± 0.52

3.29 ± 0.37

2.61 ± 0.52

  1. The radioactivity levels are expressed as SUVs
  2. Data represent the mean ± SD (n = 4)