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Table 3 Biodistribution data of control, diabetic and obese mice at room temperature, under acute cold and cold acclimation 30 min after injection of [18F]BDP-TG-chylomicron-like particles, expressed as %IA/g

From: Brown adipose tissue uptake of triglyceride-rich lipoprotein-derived fatty acids in diabetic or obese mice under different temperature conditions

  Control Diabetic Obese
21 °C (%) Acute cold (%) Cold accl (%) 21 °C (%) Acute cold (%) Cold accl (%) 21 °C (%) Acute cold (%) Cold accl (%)
Blood 3.9 ± 0.7 4.5 ± 2.6 4.3 ± 1.4 4.4 ± 0.3 4.9 ± 0.6 4.5 ± 0.3 4.9 ± 0.7 4.6 ± 2.9 4.1 ± 2.3
Heart 16.9 ± 4.1 19.9 ± 9.8 17.2 ± 3.3 23.7 ± 1.9 23.8 ± 6.6 25.5 ± 7.2 12.1 ± 1.7 11.4 ± 5.8 12.1 ± 5.7
Lung 18.0 ± 16.8 16.0 ± 5.0 9.7 ± 1.7 10.7 ± 3.9 10.2 ± 0.7 14.7 ± 12.1 5.2 ± 0.3 16.0 ± 4.9 17.0 ± 13.0
Liver 21.5 ± 2.0 23.7 ± 3.0 24.9 ± 3.6 37.4 ± 3.3 33.4 ± 2.1 38.4 ± 0.5 16.7 ± 1.2 21.5 ± 3.3 18.9 ± 3.9
Spleen 30.8 ± 16.9 32.3 ± 14.8 39.3 ± 21.3 38.7 ± 6.9 50.3 ± 9.7 33.4 ± 1.2 15.5 ± 1.9 24.8 ± 10.5 18.9 ± 3.7
Stomach 2.3 ± 1.3 3.2 ± 1.1 1.6 ± 0.3 2.7 ± 0.2 2.9 ± 1.5 1.9 ± 0.1 2.4 ± 0.7 2.0 ± 0.5 1.7 ± 1.1
Pancreas 2.2 ± 1.0 5.1 ± 3.9 2.3 ± 1.4 3.2 ± 0.8 2.9 ± 0.5 2.8 ± 0.7 1.9 ± 0.3 4.3 ± 3.3 3.0 ± 3.8
Kidneys 5.6 ± 0.5 6.3 ± 3.1 5.7 ± 1.0 9.0 ± 1.5 9.0 ± 1.5 9.9 ± 2.1 5.3 ± 0.5 6.2 ± 1.6 5.6 ± 2.0
Intestines 2.3 ± 0.4 2.2 ± 0.4 2.3 ± 0.5 3.8 ± 0.6 2.8 ± 0.3 2.7 ± 0.7 3.3 ± 0.6 2.7 ± 0.5 2.8 ± 1.0
Muscle 2.4 ± 1.1 2.0 ± 1.6 1.4 ± 0.6 1.6 ± 0.3 1.1 ± 0.6 1.2 ± 0.6 1.5 ± 0.2 1.6 ± 0.6 1.3 ± 0.3
Bone 7.1 ± 2.6 7.1 ± 3.6 5.8 ± 3.2 4.3 ± 0.9 4.4 ± 0.8 5.3 ± 1.3 9.2 ± 2.5 6.5 ± 4.8 5.2 ± 1.9
WAT 2.7 ± 1.4 3.7 ± 2.9 2.4 ± 0.9 1.9 ± 0.4 1.8 ± 1.2 1.4 ± 0.1 1.5 ± 0.9 0.8 ± 0.6 0.7 ± 0.2
Skin 1.6 ± 0.6 1.5 ± 0.7 1.5 ± 0.4 1.3 ± 0.2 1.9 ± 0.9 1.2 ± 0.2 1.1 ± 0.1 1.5 ± 0.5 1.1 ± 0.2
BAT 9.6 ± 1.7 15.1 ± 4.7 7.6 ± 1.9 8.0 ± 1.3 8.2 ± 1.4 9.2 ± 1.8 5.1 ± 0.6 8.0 ± 1.8 6.9 ± 1.4 ‬
Aorta 9.7 ± 4.5 13.1 ± 3.1 10.1 ± 6.4 4.9 ± 0.9 6.8 ± 3.3 6.0 ± 1.5 3.0 ± 2.7 6.5 ± 2.0 5.1 ± 1.0
Brain 0.6 ± 0.7 0.4 ± 0.3 0.3 ± 0.1 0.2 ± 0.0 0.2 ± 0.0 0.2 ± 0.0 0.2 ± 0.0 0.2 ± 0.1 0.4 ± 0.4
Remainder 8.0 ± 0.4 7.3 ± 0.5 7.6 ± 0.8 7.2 ± 1.0 6.6 ± 0.2 6.5 ± 0.3 6.8 ± 0.5 7.0 ± 0.9 6.9 ± 1.0