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EJNMMI Research

Table 6 Multivariate analysis of predictors of progression-free and overall survival

From: Baseline total metabolic tumor volume combined with international peripheral T-cell lymphoma project may improve prognostic stratification for patients with peripheral T-cell lymphoma (PTCL)

Variable

Progression-free survival

Overall survival

B

SE

Wald

HR (95% CI)

P value*

B

SE

Wald

HR (95% CI)

P value*

LDH level, normal/elevate

–

–

–

–

0.472

–

–

–

–

0.233

B symptoms, no/yes

–

–

–

–

0.233

–

–

–

–

0.469

ECOG PS, 0–1/ ≥ 2

–

–

–

–

0.708

–

–

–

–

0.988

BMB, negative/positive

–

–

–

–

0.932

–

–

–

–

0.999

Platelet cell count, ≥ 150 × 109/L

–

–

–

–

0.276

–

–

–

–

0.289

IPI, 0–2/3–5

–

–

–

–

0.888

–

–

–

–

0.827

PIT, 0–1/2–4

–

–

–

–

0.825

–

–

–

–

0.632

IPTCLP, 0–1/2, 3

0.947

0.310

9.351

2.577 (1.405–4.727)

0.002

0.859

0.310

7.664

2.360 (1.285–4.336)

0.006

SUVmax, low/high

–

–

–

–

0.689

–

–

–

–

0.688

TMTV, low/high

1.629

0.348

21.953

5.096 (2.579–10.072)

< 0.001

1.536

0.346

19.766

4.647 (2.361–9.148)

< 0.001

TLG, low/high

–

–

–

–

0.964

–

–

–

–

0.933

  1. Univariate analyses of factors predictive of survival in patients whose scans were evaluated using TMTV and TLG
  2. CI confidence interval, SE standard error, CI confidence interval, HR hazards ratio, LDH lactate dehydrogenase, ECOG PS Eastern Cooperative Oncology Group performance status, BMB bone marrow biopsy, IPI International Prognostic Index, PIT prognostic index for T-cell lymphoma, IPTCLP International peripheral T cell lymphoma Project, TMTV total metabolic tumor volume, TLG total lesion glycolysis
  3. *P < 0.05
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