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EJNMMI Research
Fig. 2 | EJNMMI Research

Fig. 2

From: [68Ga]ABY-028: an albumin-binding domain (ABD) protein-based imaging tracer for positron emission tomography (PET) studies of altered vascular permeability and predictions of albumin-drug conjugate transport

Fig. 2

Radiolabeling and analyses of [68Ga]ABY-028. a The major steps in the radiolabeling with 68Ga. b Size-exclusion chromatography of the reaction solution after the labeling of [68Ga]ABY-028 (UV and radio). c Reversed phase chromatography of reference precursor ABY-028 (UV) compared with the purified [68Ga]ABY-028 (UV and radio). d Analysis of [68Ga]ABY-028 binding to immobilized HSA with and without blocking using a 200-fold excess of non-labeled ABY-028. e Analysis of [68Ga]ABY-028 binding to immobilized HSA. The normalized radioactivity is plotted against the concentration of [68Ga]ABY-028

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