Table 2 Advantages and limitations of different analytical techniques applied to radiometabolite analysis
Analytical techniques | Sensitivity | Resolution | Measurement speed | Required pre-treatment | Cost |
|---|---|---|---|---|---|
Radio-TLC | High | Low | Slow | Yes | Low |
OPTLC | High | Moderate | Fast | Yes | Moderate |
Radio-HPLC | High | High | Fast | Yes | High |
Column-switching HPLC | High | High | Fast | No | High |
SPE | Moderate | Low | Fast | Usually no | Low |
Micellar chromatography | High | Low | Fast | No | Low |