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Table 2 Advantages and limitations of different analytical techniques applied to radiometabolite analysis

From: Dealing with PET radiometabolites

Analytical techniques Sensitivity Resolution Measurement speed Required pre-treatment Cost
Radio-TLC High Low Slow Yes Low
OPTLC High Moderate Fast Yes Moderate
Radio-HPLC High High Fast Yes High
Column-switching HPLC High High Fast No High
SPE Moderate Low Fast Usually no Low
Micellar chromatography High Low Fast No Low