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Fig. 5 | EJNMMI Research

Fig. 5

From: Fluorescent image-guided surgery in breast cancer by intravenous application of a quenched fluorescence activity-based probe for cysteine cathepsins in a syngeneic mouse model

Fig. 5

Image-guided surgery post intravenous injection of VGT-309. a Still images from Novadaq Spy Elite and SurgVision Explorer Air during resection of 4T1 tumors on different time points after injection of VGT-309. b White light (left) and fluorescent (middle) images of the surgical field before (upper) and after (lower) tumor removal using the Novadaq Spy Elite. H&E staining (right) histopathological analysis confirms that the tissues highlighted in the white and red squares in the middle panels are breast tumor and muscle, respectively

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