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EJNMMI Research
Fig. 4 | EJNMMI Research

Fig. 4

From: Fluorescent image-guided surgery in breast cancer by intravenous application of a quenched fluorescence activity-based probe for cysteine cathepsins in a syngeneic mouse model

Fig. 4

Microscopic fluorescent signal of VGT-309 colocalizes with tumor-infiltrated immune cells including macrophages. a A representative fluorescent image of a 4-μm-thick tumor slide from the mouse imaged 24 h after intravenous injection of VGT-309. Corresponding F4/80 immunohistochemical staining images of the areas highlighted by squares in a show b immune infiltrate containing few macrophages, c a high presence of macrophages, and d tumor cells

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