Skip to main content

Table 1 Study demographics of the included papers

From: Nuclear imaging methods for the prediction of postoperative morbidity and mortality in patients undergoing localized, liver-directed treatments: a systematic review

Author Year Country Prospective study Consecutive recruitment Tracer Patients (n) Postoperative outcome (correlated to NMT) Major/minor surgery or both
Mortality Liver failure Morbidity Liver function tests  
Bennink et al. [14] 2004 The Netherlands Yes Yes [99mTc]Tc-Meb 15 No No No Yes Both
Beppu et al. [15] 2018 Japan Yes No [99mTc]Tc-GSA 40 No No No Yes Major
Cieslak et al. [16] 2016 The Netherlands No Yes [99mTc]Tc-Meb 163 Yes Yes Yes No Major
Cieslak et al. [17] 2017 The Netherlands No Yes [99mTc]Tc-Meb 46 No Yes No No Major
Chiba et al. [18] 2017 Japan No Yes [99mTc]Tc-GSA 123 Yes Yes No No Both
Chapelle et al. [19] 2016 Belgium Yes Yes [99mTc]Tc-Meb 88 Yes Yes No No Both
Chapelle et al. [20] 2017 Belgium Yes Yes [99mTc]Tc-Meb 1881 Yes Yes No Yes Both
Chapelle et al. [21] 2017 Belgium No Yes [99mTc]Tc-Meb 140 No Yes No Yes Both
Cho et al. [22] 2017 Korea No Yes [18F]FDG 149 No Yes No No Both
Das et al. [23] 2001 Japan No Yes [99mTc]Tc-GSA 100 Yes No Yes No Both
de Graaf et al. [11] 2010 The Netherlands No Yes [99mTc]Tc-Meb 36 No No No Yes Both
de Graaf et al. [10] 2010 The Netherlands No Yes [99mTc]Tc-Meb 55 No Yes Yes Yes Major
Dinant et al. [24] 2007 The Netherlands Yes Yes [99mTc]Tc-Meb 46 Yes Yes Yes No Both
Franken et al. [25] 2020 The Netherlands No Yes [99mTc]Tc-Meb 191 Yes Yes Yes No Both
Fujioka et al. [26] 1999 Japan No No [99mTc]Tc-GSA 15 Yes No Yes No Both
Guiu et al. [27] 2017 France No Yes [99mTc]Tc-Meb 9 Yes Yes Yes Yes Major
Hayashi et al. [28] 2015 Japan No Yes [99mTc]Tc-GSA 133 Yes Yes Yes No Major
Hino et al. [29] 1997 Japan No No [99mTc]Tc-Sn colloid 47 Yes Yes No No Both
Hirai et al. [30] 2003 Japan No Yes [99mTc]Tc-GSA 30 No Yes No Yes Major
Hwang et al. [31] 1999 Japan Yes Yes [99mTc]Tc-GSA 75 No Yes No No Both2,3
Iimuro et al. [32] 2010 Japan No No [99mTc]Tc-GSA 32 No No Yes Yes Both
Jansen et al. [33] 1990 The Netherlands No No [99mTc]Tc-colloid 11 No No No Yes Both
Kaibori et al. [34] 2008 Japan Yes Yes [99mTc]Tc-GSA 191 Yes Yes No No Both
Kamohara et al. [35] 2011 Japan No No [99mTc]Tc-GSA 180 No Yes Yes No NR4
Kato et al. [36] 2018 Japan No Yes [99mTc]Tc-GSA 100 No Yes No Yes Both
Katsuramaki et al. [37] 2003 Japan No Yes [99mTc]Tc-GSA 63 No Yes Yes No Both
Kawamura et al. [38] 2008 Japan No No [99mTc]Tc-GSA 99 No Yes No Yes Both
Kim et al. [39] 1997 Japan No Yes [99mTc]Tc-GSA 30 Yes Yes Yes No Both
Kokudo et al. [40] 2002 Japan No Yes [99mTc]Tc-GSA 111 No Yes Yes No Minor
Kwon et al. [41] 1995 Japan No Yes [99mTc]Tc-GSA 36 No No No Yes Both2
Kwon et al. [42] 1997 Japan No Yes [99mTc]Tc-GSA 90 Yes No No No Both2
Kwon et al. [43] 2001 Japan No Yes [99mTc]Tc-GSA 47 Yes No No Yes Both2
Kwon et al. [44] 2004 Japan No No [99mTc]Tc-GSA 32 Yes No No Yes Both
Kwon et al. [45] 2004 Japan No No [99mTc]Tc-GSA 152 Yes Yes No No Both2
Kwon et al. [46] 2006 Japan No Yes [99mTc]Tc-GSA 178 Yes No No Yes Both2
Li et al. [47] 2003 Japan Yes No [99mTc]Tc-GSA 44 No No No Yes Both4
Mao et al. [48] 2015 China Yes No [99mTc]Tc-GSA 69 No Yes Yes Yes Both
Mitsumori et al. [49] 1998 Japan No No [99mTc]Tc-GSA 20 No Yes No Yes Both
Nakamura et al. [50] 2018 Japan No Yes [99mTc]Tc-GSA 218 No Yes No No Both
Nakano et al. [51] 1999 Japan (and France) No Yes [99mTc]Tc-GSA 18 No Yes Yes Yes Major5
Nakano et al. [52] 1999 Japan (and France) No Yes [99mTc]Tc-GSA 64 No No Yes Yes Both3
Namieno et al. [53] 1997 Japan Yes No [99mTc]Tc-PMT 8 Yes No No Yes Both
Nanashima et al. [54] 2004 Japan No No [99mTc]Tc-GSA 140 No Yes Yes No Both2
Nanashima et al. [55] 2007 Japan No Yes [99mTc]Tc-GSA 185 No Yes Yes No Both
Nanashima et al. [56] 2010 Japan No Yes [99mTc]Tc-GSA 250 No Yes Yes No Both
Nanashima et al. [57] 2013 Japan No No [99mTc]Tc-GSA 442 No Yes Yes No Both
Nanashima et al. [58] 2013 Japan No No [99mTc]Tc-GSA 67 No Yes Yes No Both2
Nanashima et al. [59] 2020 Japan No No [99mTc]Tc-GSA 229 No Yes Yes No Both
Nishikawa et al. [60] 2015 Japan No Yes [99mTc]Tc-GSA 213 Yes No Yes No Both
Nishiyama et al. [61] 2003 Japan No No [99mTc]Tc-GSA 20 Yes No No No Major
Nitta et al. [62] 2019 Japan No Yes [99mTc]Tc-GSA 60 No Yes Yes Yes Both
Okabayashi et al. [63] 2017 Japan Yes Yes [99mTc]Tc-GSA 185 Yes Yes Yes Yes Both
Okabe et al. [64] 2014 Japan Yes Yes [99mTc]Tc-GSA 625 No Yes No No Both2
Olthof et al. [65] 2017 The Netherlands No Yes [99mTc]Tc-Meb 116 Yes Yes Yes No Major
Otsuki et al. [66] 1997 Japan Yes No [11C]C-Met 11 Yes No No No Major
Rassam et al. [67] 2019 The Netherlands No Yes [99mTc]Tc-Meb 71 Yes Yes Yes No Both
Satoh et al. [68] 2003 Japan No No [99mTc]Tc-GSA 57 Yes Yes No No Both
Serenari et al.6 [69] 2018 Argentina No Yes [99mTc]Tc-Meb 20 Yes Yes No No Major
Serenari et al. [70] 2019 Italy No Yes [99mTc]Tc-Meb 27 No Yes No No Major
Shimizu et al. [71] 2010 Japan Yes No [99mTc]Tc-GSA 86 No No No Yes Both2
Sparrelid et al .[72] 2017 Sweden Yes No [99mTc]Tc-Meb 9 No No No Yes Major
Sugai et al. [73] 2000 Japan No No [99mTc]Tc-GSA 11 No Yes Yes Yes Major
Sumiyoshi et al. [74] 2016 Japan No No [99mTc]Tc-GSA 30 No Yes No Yes Major
Sumiyoshi et al. [75] 2018 Japan No Yes [99mTc]Tc-GSA 13 Yes Yes Yes No Both3
Takeuchi et al. [76] 1999 Japan No Yes [99mTc]Tc-GSA 40 Yes No Yes Yes Both
Tanabe et al. [77] 1989 Japan No No [198Au]Au colloid + [99mTc]Tc-Sn colloid 21 Yes No Yes No Both
Tanaka et al. [78] 1999 Japan No No [99mTc]Tc-GSA 44 No No No Yes Both
Tanaka et al. [79]7 2013 Japan Yes Yes [99mTc]Tc-GSA 247 Yes Yes No No Major
Tanaka et al. [80] 2015 Japan No No [99mTc]Tc-GSA 64 No No No Yes Both
Tanoue et al. [81] 2019 Japan No No [99mTc]Tc-GSA 247 No Yes Yes Yes Both
Truant et al. [82] 2016 France No No [99mTc]Tc-Meb 5 Yes Yes No Yes Major
Truant et al. [83] 2017 France Yes Yes [99mTc]Tc-Meb 100 Yes Yes No Yes Major
Uetake et al. [84] 1999 Japan No No [99mTc]Tc-GSA 13 No No Yes Yes Both
van den Esschert et al. [85] 2009 The Netherlands No Yes [99mTc]Tc-Meb 23 No No No Yes Major
Wakamatsu et al. [86] 2010 Japan Yes Yes [99mTc]Tc-GSA 70 No No No Yes Minor
Yamao et al. [87] 2019 Japan No Yes [99mTc]Tc-GSA 283 Yes No Yes No NR3,4
Yano et al. [88] 2017 Japan No No [99mTc]Tc-GSA 200 No Yes Yes Yes Both
Yano et al. [89] 2018 Japan No Yes [99mTc]Tc-GSA 165 Yes No No No Both
Yoshida et al. [90] 2012 Japan No No [99mTc]Tc-GSA 256 No Yes No Yes Both
Yoshida et al. [91] 2014 Japan No Yes [99mTc]Tc-GSA 95 No No No Yes Both2
Yumoto et al. [92] 1994 Japan Yes No [99mTc]Tc-GSA 26 Yes Yes No Yes Both2
Yumoto et al. [93] 2010 Japan No Yes [99mTc]Tc-GSA 101 Yes Yes No Yes Both
  1. NMT nuclear medicine test, [99mTc]Tc-Meb 99mTc-labeled mebrofenin, [99mTc]Tc-GSA 99mTc-labeled galactosyl human serum albumin, [18F]FDG [18F]fluorodeoxyglucose, [99mTc]Tc-Sn colloid 99mTc-labeled sulfur colloid, [99mTc]Tc-colloid 99mTc-labeled colloid, [99mTc]Tc-PMT 99mTc-labeled pyridoxyl-5-methyltryptophan, [11C]C-Met L-[methyl-11C]-methionine, [198Au]Au colloid + [99mTc]Tc-Sn colloid radioactive colloidal gold and 99mTc-labeled sulfur colloid
  2. 1Including 88 patients from a prior study from Chapelle et al. [19] to whom they compare the results to and conduct new analyses on these patients
  3. 2Both major and minor surgery but analyzed separately in the paper
  4. 3Includes other procedures with the purpose to remove diseased liver parenchyma as well, not only liver resection
  5. 4The type of liver resection was not defined explicitly
  6. 5Pancreaticoduodenectomy with reconstructive pancreaticojejunostomy and hepaticojejunostomy, classified as major surgery
  7. 6Hepatobiliary scintigraphy performed before stage 2 of the ALPPS procedure
  8. 7Abstract