Predictive value of quantitative 18F-FDG-PET radiomics analysis in patients with head and neck squamous cell carcinoma

Table 3 Predictive accuracy of clinical parameters, PET-parameters, and radiomics factors separately and combined for the prediction of locoregional recurrence, metastasis, and death

	Recurrence prediction				Metastasis prediction				Overall survival prediction
	Patients	Recurrences	Concordance index	SE	Patients	Distant metastasis	Concordance index	SE	Patients	Deaths	Concordance index	SE
Clinical parameters T-stage, N-stage, HPV-status, Smoking (PY)	103	27	0.699	0.049	103	10	0.690	0.097	103	37	0.691	0.043
PET parameters SUVmax, SUVmean, SUVpeak, TLG, MATV	103	27	0.616	0.065	103	10	0.759	0.062	103	37	0.711	0.041
Radiomics parameters Factor 1 to 8	103	27	0.716	0.055	103	10	0.746	0.079	103	37	0.714	0.05
Combined clinical + PET parameters	103	27	0.758	0.05	103	10	0.822	0.047	103	37	0.744	0.042
Combined clinical + radiomics	103	27	0.770	0.043	103	10	0.831	0.066	103	37	0.749	0.047
Combined clinical + PET + radiomics	103	27	0.796	0.045	103	10	0.945	0.029	103	37	0.750	0.046