Fig. 1

An overview of the radiomics workflow including a delineation, b extracting of intensity, texture, morphologic, and shape radiomics features. c The removal of redundancy of highly correlated features (Pearson r > 0.95) and the construction of factors. d The construction of prediction models with clinical, first-order PET-features, and/or radiomic factors and the risk-stratification into a high/medium/low risk for developing an event based on the constructed prediction models