P1 | P2 | P3 | P4 | P5* (extended) | P5* (extended) | P5* (actual) | ||
---|---|---|---|---|---|---|---|---|
First diagnosis (days before treatment) | 16 | 35 | 35 | 33 | 28 | |||
Pre-treatment diagnosis | Vascular neoplasm vs vascular anomaly | Astrocytoma† | Low-grade glioma | Glial neoplasm | Astrocytoma† | |||
Infused activity (GBq) | 0.0183 | 0.0478 | 0.0351 | 0.0414 | 0.0486 | – | – | |
Treatment days post-calibration | 11 | 5 | 10 | 5 | 8 | |||
Volume of embolic (mL) | 0.0014 | 0.00076 | 0.0021 | 0.00066 | 0.0017 | |||
Pre-treatment mass vol (mL) | 2.76 | 5.82 | 3.53 | 8.66 | 8.48 | – | – | |
Single compartment dose (Gy) | 34.9 | 63.7 | 45 | 45.2 | 62.2 | – | – | |
Dosimetry method | PET/CT | PET/CT | PET/CT | PET/CT | PET/CT | MicroCT | MicroCT | |
Mass | Mean dose (Gy) | 45.5 | 57.6 | 58.1 | 45.4 | 64.1 | 76.7 | 11.3 |
D10 (Gy) | 95.2 | 122.9 | 91.5 | 94.8 | 137.0 | 131.4 | 19.3 | |
D30 (Gy) | 58.6 | 70.2 | 70.8 | 54.9 | 80.0 | 80.8 | 11.9 | |
D50 (Gy) | 35.7 | 37.6 | 55.8 | 36.1 | 52.6 | 59.4 | 8.73 | |
D70 (Gy) | 22.6 | 20.2 | 41.6 | 24.2 | 27.9 | 44.8 | 6.58 | |
D90 (Gy) | 8.5 | 10.0 | 26.9 | 8.1 | 7.2 | 30.6 | 4.49 | |
V30 | 58.3 | 55.9 | 85.4 | 60.4 | 68.9 | 90.6 | 3.28 | |
V50 | 37.2 | 40.6 | 57.8 | 34.5 | 52.6 | 62.4 | 0.96 | |
V60 | 28.9 | 34.9 | 44.0 | 26.8 | 43.5 | 49.3 | 0.64 | |
V80 | 16.5 | 26.3 | 20.3 | 15.8 | 30.0 | 30.6 | 0.34 | |
V100 | 9.1 | 19.0 | 6.4 | 8.4 | 19.3 | 10.3 | 0.22 | |
Hemisphere | Mean dose (Gy) | 33.8 | 65.3 | 41.1 | 45.0 | 61.4 | 41.4 | 6.08 |
V20 | 54.8 | 74.6 | 68.2 | 65.5 | 77.5 | 63.1 | 3.39 | |
V30 | 40.8 | 66.4 | 57.6 | 50.8 | 67.1 | 49.8 | 1.21 | |
V50 | 23.0 | 52.2 | 37.1 | 33.6 | 49.8 | 28.8 | 0.39 | |
V60 | 17.3 | 44.7 | 27.7 | 27.3 | 41.7 | 21.5 | 0.27 | |
Cortex | Mean dose (Gy) | 15.4 | 27.6 | 19.2 | 16.7 | 33.3 | – | – |
V20 | 24.1 | 33.3 | 32.6 | 24.1 | 43.8 | – | – | |
V30 | 17.7 | 28.2 | 25.6 | 17.7 | 36.5 | – | – | |
V50 | 10.1 | 21.3 | 15.3 | 10.7 | 25.5 | – | – | |
V60 | 7.4 | 18.0 | 11.3 | 8.3 | 21.0 | – | – | |
T:N‡ | 2.96 | 2.08 | 3.02 | 2.71 | 1.93 | – | – |