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Table 3 Test-retest metrics of [18F]FE-PE2I PET measurements (n = 9)

From: Reliability of dopamine transporter PET measurements with [18F]FE-PE2I in patients with Parkinson’s disease

Region

PET 1 (BPND), COV (%)

PET 2 (BPND), COV (%)

AbsVar (%)

ICC

MDD

Powered detectable % change

Striatum

1.55 ± 0.33, 21.1

1.56 ± 0.32, 20.5

5.3

0.95 (0.82–0.989)

0.195

− 8.3

Caudate

1.84 ± 0.55, 29.9

1.88 ± 0.59, 31.4

6.0

0.97 (0.89–0.99)

0.264

− 8.9

Putamen

1.26 ± 0.32, 25.3

1.25 ± 0.22, 17.8

7.5

0.91 (0.68–0.98)

0.225

− 11.9

Ventral striatum

2.21 ± 0.53, 23.9

2.13 ± 0.38, 17.9

6.5

0.89 (0.61–0.97)

0.426

− 12.1

Substantia nigra

0.72 ± 0.17, 23.2

0.72 ± 0.1, 14.5

10.6

0.74 (0.24–0.93)

0.194

− 17.9

  1. COV coefficient of variability (SD/mean × 100), AbsVar absolute variability, ICC intraclass correlation coefficient, MDD minimum detectable difference covering 95% of the distribution of test-retest differences, Powered detectable % change based on measured effect size and power 0.8